How much saline to put in nebulizer

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Saline solution in nebulizer to help move mucous. Answer View More. Is hypertonic saline solution via nebuliser effective and safe for the treatment of infants with acute bronchiolitis, compared to normal saline solution? Acute bronchiolitis is the most common lower respiratory tract infection in children aged up to two years.

Bronchiolitis occurs when small structures bronchioles leading to the lungs become infected, causing inflammation, swelling, and mucus production. This makes breathing difficult, especially in very young children, who develop coughs and wheezing.

Because bronchiolitis is usually caused by a virus, drug treatment is usually not effective. Hypertonic saline sterile salt water solution breathed in as a fine mist using a nebuliser may help relieve wheezing and breathing difficulty. We included a total of 28 trials involving infants with acute bronchiolitis. Nebulised hypertonic saline may reduce hospital stay by 10 hours in comparison to normal saline for infants admitted with acute bronchiolitis.

We found that 'clinical severity scores', which are used by doctors to assess patient health, for children treated as outpatients or in hospital improved when administered nebulised hypertonic saline compared to normal saline. We found only minor and spontaneously resolved adverse effects from the use of nebulised hypertonic saline when given with treatment to relax airways bronchodilators.

Reductions in hospital stay were smaller than previously thought. However, an average reduction of 10 hours in the length of hospital stay for infants is significant because bronchiolitis usually has a short duration.

Nebulised hypertonic saline appears to be safe and widely available at low cost. The quality of the evidence was low to moderate: there were inconsistencies in results among trials and risk of bias in some trials. Future large trials are therefore needed to confirm the benefits of nebulised hypertonic saline for children with bronchiolitis treated as outpatients and in hospital.

Nebulised hypertonic saline may modestly reduce length of stay among infants hospitalised with acute bronchiolitis and improve clinical severity score. Treatment with nebulised hypertonic saline may also reduce the risk of hospitalisation among outpatients and emergency department patients. However, we assessed the quality of the evidence as low to moderate. Airway oedema swelling and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis.

This is an update of a review first published in , and previously updated in and